Research
Research at the ZNP
The knowledge on pathological processes in the central nervous system is fundamental for the development of effective therapeutic strategies. Main focus of our research is the mechanisms and molecular basis of synapse and
nerve cell dysfunction in neurodegenerative diseases.
Here various different state of art approaches are applied both in animal models as well as human tissue from our brain bank. Moreover in close collaboration with clinical partners we develop new diagnostic tools in the diagnosis, monitoring and treatment of brain tumors.
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The AG Translational Neurodegeneration (Head: Prof. Dr. J. Herms) applies high end imaging and electrophysiological techniques in mouse models of neurodegenerative diseases, e.g. Alzheimer's and Parkinson's disease in order to understand the mechanism of synaptic failure in these conditions.
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Our research focuses on clinical and experimental neuropathology with a special focus on brain tumor patients. The major aim is the development of novel diagnostic tools, which help to classify tumors on the one hand, on the other hand we develop therapy monitoring algorithms for the prediction of clinical courses.
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The goal of our research group is to identify new therapeutic options for patients with previously incurable brain tumours. Our current focus is on drug testing in the context of individualized therapeutic approaches for children with brain tumors.
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The research focus „Applied Bioinformatics in Neurodegeneration” aims to identify the molecular mechanisms that lead to the degeneration of cells in the central nervous system.
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